Endocrine Abstracts

Background: Angiogenesis and lymphangiogenesis are involved in growth and metastatic spread of tumours. Vascular endothelial growth factor-A (VEGF-A) and fibroblast growth factor-2 (FGF-2) play a key role in angiogenesis through proliferation of endothelial cells. VEGF-C has been identified as the molecular link between tumour lymphangiogenesis and metastasic spread.Objective: To (1) analyse microvascular density (MVD) and lymphatic vascular density (LVD...

Background: Growth of solid tumours is angiogenesis dependent. Vascular endothelial growth factor (VEGF-A) and fibroblast growth factor-2 (FGF-2) are potent endothelial cell mitogens that play a central role in angiogenesis. Very recently intratumoral lymphangiogenesis has been reported. There are currently no data on the presence of angiogenesis or lymphangiogenesis in parathyroid proliferative lesions compared to normal glands.Objectives: (1) To analyse microvascular den...